This antibody recognizes intact Human Osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-42 or intact Bovine Osteocalcin.
无交叉反应
牛, 小鼠, 大鼠
交叉反应 (详细)
Species reactivity (tested):Human.
产品特性
Synonyms: Bone Gla protein, BGLAP, Gamma-carboxyglutamic acid-containing protein
纯化方法
Purified IgG prepared by affinity chromatography on Protein A
ELISA. This antibody may be used in combination with ABIN316667 or ABIN180921 inSandwich ELISA assays. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
有效期
12 months
抗原
Osteocalcin (BGLAP)
别名
Osteocalcin
背景
Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.Synonyms: BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein