Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) 抗体
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Quick Overview for Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) 抗体 (ABIN307154)
抗原
See all Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Human G-Protein Coupled Receptor 94
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交叉反应
- 人
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产品特性
- Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined. Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Synthetic peptide derived from human GPCR94.
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anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (AA 1-49) antibody
P2RY13 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2H1G9 unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (AA 1-49) antibodyP2RY13 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (C-Term) antibodyP2RY13 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (Internal Region) antibodyP2RY13 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (AA 162-190) antibodyP2RY13 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (Extracellular Domain) antibodyP2RY13 适用: 人, 兔, Cow, 猴, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) antibodyP2RY13 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4725 unconjugated Recombinant Antibody
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) antibodyP2RY13 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (2nd Cytoplasmic Loop), (AA 119-134) antibodyKO Validated P2RY13 适用: 人 WB, IHC, FACS, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (AA 266-281), (Extracellular), (Loop 3) antibodyP2RY13 适用: 小鼠 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)
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别名
- G-Protein Coupled Receptor 94
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背景
- P2Y Purinoceptor 13, P2Y13, G-protein coupled receptor 86, GPCR94, GPCR86
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UniProt
- Q9BPV8
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途径
- cAMP Metabolic Process
抗原
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