LASS1 抗体
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北京 101111
Quick Overview for LASS1 抗体 (ABIN307130)
抗原
See all LASS1 (CERS1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Human Lass1 (Cross reacts with GDF1)
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交叉反应
- 人
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产品特性
- LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane, LAss1 is a multi-pass membrane protein.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Synthetic peptide derived from the human Lass1 protein.
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亚型
- IgG
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anti-Ceramide Synthase 1 (CERS1) (AA 301-350) antibody
CERS1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Ceramide Synthase 1 (CERS1) (AA 301-350) antibodyCERS1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ceramide Synthase 1 (CERS1) (AA 1-52) antibodyCERS1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Synthase 1 (CERS1) (Middle Region) antibodyCERS1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Synthase 1 (CERS1) (Internal Region) antibodyVerified CERS1 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Ceramide Synthase 1 (CERS1) (C-Term) antibodyCERS1 适用: 人, 小鼠, 大鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Antibody can be used for Western blotting (1-5 μg/mL starting dilution). Other uses not yet tested. Only reacts with human Lass1 protein. Also cross reacts with human GDF1. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))
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别名
- Lass1 (Cross reacts with GDF1)
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背景
- LAG1 longevity assurance homolog 1, UOG-1 protein, LAG1, LASS1, LAG1 longevity assurance homolog 1 (LASS 1)
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UniProt
- P27544
抗原
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