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MMP3 抗体 (C-Term)

This anti-MMP3 antibody is a 小鼠 单克隆 antibody detecting MMP3 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN307118
发货至: 中国

Quick Overview for MMP3 抗体 (C-Term) (ABIN307118)

抗原

See all MMP3 抗体
MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

适用

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宿主

  • 144
  • 100
  • 2
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  • 1
小鼠

克隆类型

  • 126
  • 125
单克隆

标记

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This MMP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

1B4
  • 抗原表位

    • 30
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    C-Term

    交叉反应

    产品特性

    SL-1, Matrix metalloproteinase-3, MMP-3, Transin-1,The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including Collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

    纯化方法

    Protein A/G Chromatography

    免疫原

    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminus of the human MMP3 protein and mouse myeloma Ag8563 cells.

    亚型

    IgG1
  • 应用备注

    Antibody can be used for Western blotting (1-2 μg/mL) and immunohistochemistry on formlin-fixed paraffin-embedded tissue sections (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

    限制

    仅限研究用
  • 缓冲液

    Provided as solution in phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

    别名

    Matrix Metalloproteinase 3 (MMP3)
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