MMP1 抗体 (C-Term)
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北京 101111
Quick Overview for MMP1 抗体 (C-Term) (ABIN307116)
抗原
See all MMP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
- MMP1, MMP-1, CLG, CLGN, Matrix metallopeptidase 1, Interstitial collagenase,The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.
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纯化方法
- Protein A/G Chromatography
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免疫原
- Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminus of the human MMP1 protein and mouse myeloma Ag8563 cells.
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亚型
- IgG1
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anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) antibody
MMP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) antibodyMMP1 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) antibodyMMP1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6A5 unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 169-464) antibodyMMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 20-280) antibodyMMP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (N-Term) antibodyMMP1 适用: 人, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (C-Term) antibodyMMP1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) antibodyMMP1 适用: 人 WB, IHC (p), PLA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 317-347) antibodyMMP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (C-Term) antibodyMMP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Antibody can be used for Western blotting (1-2 μg/mL) and immunohistochemistry on formalin-fixed paraffin-embedded tissues (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
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别名
- Matrix Metalloproteinase 1 (MMP1)
抗原
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