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Netrin 1 抗体

NTN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN307033
发货至: 中国
  • 抗原 See all Netrin 1 (NTN1) 抗体
    Netrin 1 (NTN1)
    适用
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    宿主
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    克隆类型
    • 61
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    多克隆
    标记
    • 39
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    This Netrin 1 antibody is un-conjugated
    应用范围
    • 53
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    Western Blotting (WB)
    交叉反应
    Cat, Cow, 人, Macaque, 小鼠, 大鼠
    产品特性
    Netrin 1, NTN1,Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis. Netrin 1s main receptor is DCC (deleted in colorectal cancer- a putative tumor suppressor gene whose expression is lost in numerous cancers). DCC belongs to the so-called family of dependence receptors. These receptors induce apoptosis when their ligand is absent, thus conferring a state of cellular dependence on Netrin 1 availability. The DCC/netrin-1 duo regulates neuron survival during nervous system development. The mechanism(s) by which Netrin 1/ DCC triggers cell death are still unknown. The localization of DCC to lipid rafts appears to be a prerequisite for its proapoptotic activity.
    纯化方法
    Ammonium Sulfate Precipitation
    免疫原
    Synthetic peptide derived from the human Netrin 1 protein
    亚型
    IgG
    Top Product
    Discover our top product NTN1 Primary Antibody
  • 应用备注
    Antibody can be used for Western blotting (0.5-2 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    Netrin 1 (NTN1)
    别名
    Netrin 1 (NTN1 产品)
    别名
    ntn1-A antibody, Netrin-1 antibody, NTN1 antibody, unc-6 antibody, MGC147073 antibody, NTN1L antibody, AI561871 antibody, BC019633 antibody, netrin-1 antibody, netrin 1 L homeolog antibody, netrin 1 antibody, ntn1.L antibody, NTN1 antibody, ntn1 antibody, Ntn1 antibody
    NCBI登录号
    NP_004813
    途径
    Regulation of Cell Size
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