Netrin 1 抗体
Quick Overview for Netrin 1 抗体 (ABIN307033)
抗原
See all Netrin 1 (NTN1) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- Cat, Cow, 人, Macaque, 小鼠, 大鼠
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产品特性
- Netrin 1, NTN1,Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis. Netrin 1s main receptor is DCC (deleted in colorectal cancer- a putative tumor suppressor gene whose expression is lost in numerous cancers). DCC belongs to the so-called family of dependence receptors. These receptors induce apoptosis when their ligand is absent, thus conferring a state of cellular dependence on Netrin 1 availability. The DCC/netrin-1 duo regulates neuron survival during nervous system development. The mechanism(s) by which Netrin 1/ DCC triggers cell death are still unknown. The localization of DCC to lipid rafts appears to be a prerequisite for its proapoptotic activity.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Synthetic peptide derived from the human Netrin 1 protein
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亚型
- IgG
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anti-Netrin 1 (NTN1) (C-Term) antibody
Verified NTN1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 501-604) antibodyNTN1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 181-195), (Secreted) antibodyNTN1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 186-478) antibodyNTN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) antibodyMicroarray verified NTN1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB935839 unconjugated
anti-Netrin 1 (NTN1) antibodyMicroarray verified NTN1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB577874 unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Antibody can be used for Western blotting (0.5-2 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Netrin 1 (NTN1)
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别名
- Netrin 1
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NCBI登录号
- NP_004813
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途径
- Regulation of Cell Size
抗原
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