SPTLC1 抗体
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北京 101111
Quick Overview for SPTLC1 抗体 (ABIN307030)
抗原
See all SPTLC1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Human Serine Palmitoyltransferase 1
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交叉反应
- 人
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产品特性
- Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Synthetic peptide derived from the human serine palmitoyltransferase enzyme.
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亚型
- IgG
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应用备注
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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别名
- Serine Palmitoyltransferase 1
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背景
- Long chain base biosynthesis protein 1, LCB-1, LCB1, Serine-palmitoyl-CoA transferase 1, SPT1, SPT 1, SPT-1
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UniProt
- O15269
抗原
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