NPDC1 抗体
Quick Overview for NPDC1 抗体 (ABIN306963)
抗原
See all NPDC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Monoclonal Anti-NPDC-1 (mouse IgG1 isotype) is derived from the hybridoma 16E4 produced by immunizing mice with the peptide SLGSPVSSDPVHMS (Gene ID: 56654).
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptional events mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.
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纯化方法
- Ion-exchange chromatography
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免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with a synthetic peptide SLGSPVSSDPVHMS derived from human NPDC-1 protein (Gene ID: 56654) and mouse myeloma cells.
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亚型
- IgG1
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anti-Neural Proliferation, Differentiation and Control, 1 (NPDC1) (AA 75-180) antibody
NPDC1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neural Proliferation, Differentiation and Control, 1 (NPDC1) (Internal Region) antibodyNPDC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neural Proliferation, Differentiation and Control, 1 (NPDC1) (AA 189-238) antibodyNPDC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neural Proliferation, Differentiation and Control, 1 (NPDC1) (Internal Region) antibodyNPDC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neural Proliferation, Differentiation and Control, 1 (NPDC1) (Internal Region) antibodyNPDC1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neural Proliferation, Differentiation and Control, 1 (NPDC1) (N-Term) antibodyNPDC1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Neural Proliferation, Differentiation and Control, 1 (NPDC1) (N-Term) antibodyNPDC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neural Proliferation, Differentiation and Control, 1 (NPDC1) (Center) antibodyNPDC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Antibody can be used for Western blotting (1:1000 dilution). Optimal concentration should be evaluated by serial dilutions. Monoclonal Anti-NPDC-1 recognizes human NPDC-1 by immunoblotting (34-40 kDa).
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限制
- 仅限研究用
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缓冲液
- 20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
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别名
- NPDC-1
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UniProt
- Q8WXX4
抗原
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