Ceramide Kinase (rProtein-Full Length) 抗体
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北京 101111
Quick Overview for Ceramide Kinase (rProtein-Full Length) 抗体 (ABIN306953)
抗原
适用
宿主
克隆类型
应用范围
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原理
- Rabbit anti Human Ceramide Kinase (rProtein-Full Length)
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交叉反应
- 人
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产品特性
- Sphingolipids and their metabolic products, including ceramide, sphingosine, and sphingosine-1-phosphate (S1P),1 are important signaling molecules in many biological processes. Ceramide has been is one of the key elements regulating apoptotic responses. Ceramide has been reported as a regulator of several protein kinases and phosphatases, including ceramide-activated protein kinase, protein phosphatase, and protein kinase C. Sphingosine, a metabolite of ceramide, might also play a role in mitochondria-mediated apoptosis. Sphingosine inhibits several protein kinases, including protein kinase C and Ca2 -calmodulin-dependent kinase II. S1P regulates many biological processes, including mitogenesis, differentiation, migration, and suppression of apoptosis.
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应用备注
- Antibody can be used for Western blotting (1-10 μg/mL). Can also be used for ELISA. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Ceramide Kinase (rProtein-Full Length)
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背景
- Acylsphingosine kinase, hCERK, Lipid kinase 4, LK4
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UniProt
- Q8TCT0
抗原
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