Adiponectin Receptor 2 抗体 (C-Term)
Quick Overview for Adiponectin Receptor 2 抗体 (C-Term) (ABIN306947)
抗原
See all Adiponectin Receptor 2 (ADIPOR2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
- Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2, PAQR2,ADR2 functions as a receptor for globular and full-length adiponectin (APM1), which is an essential hormone secreted by adipocytes that acts as an antidiabetic. ADR2 is also probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. ADR2 mediates an increase in AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin and has some intermediate-affinity receptor activity for both globular and full-length adiponectin. ADR2 may form homo and heteromultimers.
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纯化方法
- Ammonium sulfate precipitation
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免疫原
- Rabbits were immunized with a synthetic peptide near the C terminus of human adiponectin receptor 2 proteins
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应用备注
- Antibody can be used for Western blotting (5-10 μg/mL) and ELISA. Other applications not yet tested. Cross reacts with Human ADR1. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Adiponectin Receptor 2 (ADIPOR2)
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别名
- Adiponectin Receptor 2
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UniProt
- Q86V24
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途径
- AMPK Signaling
抗原
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