Adiponectin Receptor 1 抗体 (N-Term)
Quick Overview for Adiponectin Receptor 1 抗体 (N-Term) (ABIN306945)
抗原
See all Adiponectin Receptor 1 (ADIPOR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人
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产品特性
- Adiponectin receptor protein 1, Progestin and adipoQ receptor family member I, ADIPOR1, PAQR1,CGI-45,Alzheimer's disease (AD) is characterized by formation of plaques of amyloid beta peptide (Abeta). Autosomally-inherited AD had been shown only in connection with coding sequence mutations. Likely transcription factors whose mutation can cause loss of function are ADR1, MIG1, and PuF, and for gain of function, E12/E47, ITF-2, and RFX2. Adr1 controls the expression of genes required for ethanol, glycerol, and fatty acid utilization (in yeast). Adr1 can act directly on the promoters of ADH2, ACS1, GUT1, CTA1, and POT1. The yeast homolog of the AMP-activated protein kinase, Snf1, promotes Adr1 chromatin binding in the absence of glucose, and the protein phosphatase complex, Glc7.Reg1, represses its binding in the presence of glucose. A post-translational process is invloved in the regulation of Adr1 binding. Chromatin binding by Adr1 is not the only step in ADH2 transcription that is regulated by glucose repression, Adr1 can bind to chromatin in repressed conditions in the presence of hyperacetylated histones. In yeast, nuclear extracts prepared from glucose-repressed and glucose-derepressed cells are equally capable of supporting miniAdr1-dependent transcription and pre-initiation complex formation.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Synthetic peptide near the N terminus of human Adiponectin Receptor 1 protein.
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anti-Adiponectin Receptor 1 (ADIPOR1) (C-Term) antibody
ADIPOR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin Receptor 1 (ADIPOR1) (AA 241-270) antibodyADIPOR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin Receptor 1 (ADIPOR1) (AA 1-63) antibodyADIPOR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin Receptor 1 (ADIPOR1) (AA 1-136) antibodyADIPOR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin Receptor 1 (ADIPOR1) (AA 305-331), (C-Term) antibodyADIPOR1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22485 unconjugated
anti-Adiponectin Receptor 1 (ADIPOR1) (AA 1-136) antibodyADIPOR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin Receptor 1 (ADIPOR1) (C-Term) antibodyADIPOR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin Receptor 1 (ADIPOR1) antibodyADIPOR1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin Receptor 1 (ADIPOR1) (AA 72-136) antibodyADIPOR1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C8 unconjugated
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应用备注
- Antibody can be used for Western blotting (5-10 μg/mL) and ELISA. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Adiponectin Receptor 1 (ADIPOR1)
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别名
- Adiponectin Receptor 1
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UniProt
- Q96A54
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途径
- AMPK Signaling
抗原
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