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SPHK1 抗体 (C-Term)

This anti-SPHK1 antibody is a 兔多克隆 antibody detecting SPHK1 in WB 和 ELISA. Suitable for 人.

Western blot analysis using Sphingosine Kinase 1 antibody at a dilution of 1:400 on MDBK cell lysate at 1:75,000. (SPHK1 抗体 (C-Term))

1 image

产品编号 ABIN306932

发货至: 中国

Quick Overview for SPHK1 抗体 (C-Term) (ABIN306932)

抗原

See all SPHK1 抗体

SPHK1 (Sphingosine Kinase 1 (SPHK1))

适用

96
42
38
9
2
2
2
2
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

57
6
4
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1

This SPHK1 antibody is un-conjugated

应用范围

71
39
24
22
13
13
11
11
7
4
3
3
2
2

Western Blotting (WB), ELISA

Discover our top product SPHK1 Primary Antibody

抗原表位
15

9

7

7

7

7

6

5

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

交叉反应

Cow, 人, 小鼠, 大鼠

产品特性

EC 2.7.1, SK 1, SPK 1, SPHK1, Gene name: SPHK1 or SPHK or SP,Sphingosine Kinase 1 (Sphk1) catalyzes the phosphorylation of sphingosine to sphingosine 1-phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors). These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide range of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).

纯化方法

Antigen Immunoaffiinity Purification

免疫原

Rabbits were immunized with a synthetic peptide derived from the C-terminal of human Sphingosine Kinase 1

亚型

IgG
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibody
SPHK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibody
SPHK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03621 unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343) antibody
SPHK1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibody
SPHK1 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 148-398) antibody
SPHK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibody
SPHK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 50-384) antibody
SPHK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30), (N-Term) antibody
SPHK1 适用: 人 WB 宿主: 兔 Polyclonal RB3619 unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 59-89) antibody
SPHK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30) antibody
SPHK1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Antibody can be used for Western blotting (1:400 dilution) and ELISA. Other applications not yet tested. Optimal concentration should be evaluated by serial dilutions.

限制

仅限研究用
状态

Liquid

缓冲液

Provided as ligand affinity purified antibody in phosphate buffered saline with 0.08 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
抗原

SPHK1 (Sphingosine Kinase 1 (SPHK1))

别名

Sphingosine Kinase 1

UniProt

Q9NYA1

途径

VEGF Signaling

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