DNA Adenine Methylase 抗体
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北京 101111
Quick Overview for DNA Adenine Methylase 抗体 (ABIN306930)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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亚型
- IgG1
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应用备注
- Antibody can be used for Western blotting (5-10 ug/ml). Other applications not yet evaluated.
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限制
- 仅限研究用
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浓度
- 1 mg/ml
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储存条件
- -20 °C
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- DNA Adenine Methylase
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背景
- DNA adenine methylase (DAM) is an enzyme that methylates adenine residues in the 4-base pair DNA sequence, GATC. This methylation reaction has been shown to be crucial in a variety of cellular processes in bacteria. These include (i) the control of initiation of DNA replication (GATC occurs 11 times in the highly conserved bacterial origin of replication sequence), (ii) methyl-directed mismatch repair, (iii) control of transposition of certain transposable DNA elements, and (iv) control of gene expression. With regard to gene expression, the recent report by Heithoff et al. (Science, 284:967-970, 1999) showed that the deletion of the DAM gene rendered Salmonella typhimurium totally avirulent. Synonyms: DAM.
抗原
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