SNAP25 抗体
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北京 101111
Quick Overview for SNAP25 抗体 (ABIN306924)
抗原
See all SNAP25 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 小鸡, Cow, 人, 猴, 小鼠, 大鼠
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产品特性
- Synaptosome-Associated Protein of 25 kDa,SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that plays an essential role in synaptic vesicle fusion and exocytosis. It is involved in the molecular regulation of neurotransmitter release. It is thought to play an important role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. SNAP25 exists as two alternatively spliced isoforms, SNAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells. These two isoforms differ by 9 amino acids in the central portion of the protein.
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纯化方法
- Protein A/G Chromatography
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免疫原
- Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with rat brain synaptosomal membranes and mouse NS1 cells.
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亚型
- IgG1
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应用备注
- Antibody can be used for Western blotting (1-5 μg/mL), immunocytochemistry and immunohistochemistry on paraformaldehyde fixed CNS tissues (1-5 μg/mL). Does not stain reduced proteins. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
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别名
- SNAP25
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UniProt
- P60880
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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