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Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) 抗体

The 兔 多克隆 anti-Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) antibody (ABIN306909) specifically detects Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) in WB. The antibody is reactive with 人 samples.
产品编号 ABIN306909
发货至: 中国
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Quick Overview for Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) 抗体 (ABIN306909)

抗原

Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4)

适用

宿主

克隆类型

多克隆

应用范围

Western Blotting (WB)
  • 抗原表位

    N-Term

    原理

    Rabbit anti Human Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) CT

    交叉反应

    产品特性

    EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor and leukocyte containing tissues.

    纯化方法

    Ammonium Sulfate Precipitation

    免疫原

    Antibody raised against a unique synthetic peptide derived from the N-terminal of the human EDG4 protein. Antigen sequence differs in mouse and rat by one amino acid.

    亚型

    IgG
  • 应用备注

    This antibody can be used for Western blotting (5-10 μg/mL). Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate). Optimal concentration should be evaluated by serial dilutions.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4)

    UniProt

    Q9HBW0
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