Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) 抗体
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Quick Overview for Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) 抗体 (ABIN306909)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- N-Term
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原理
- Rabbit anti Human Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) CT
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交叉反应
- 人
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产品特性
- EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor and leukocyte containing tissues.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Antibody raised against a unique synthetic peptide derived from the N-terminal of the human EDG4 protein. Antigen sequence differs in mouse and rat by one amino acid.
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亚型
- IgG
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应用备注
- This antibody can be used for Western blotting (5-10 μg/mL). Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4)
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UniProt
- Q9HBW0
抗原
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