HIRA 抗体
Our Local Distributor
北京 101111
Quick Overview for HIRA 抗体 (ABIN306897)
抗原
See all HIRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
亚型
- IgG
-
-
-
-
应用备注
- Antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Mav108 cells expressing recombinant TUP1 protein.
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/ml
-
储存条件
- -20 °C
-
-
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
-
别名
- TUP1
-
背景
- Yeast Tup 1p-Ssn6p repressor complex represents a novel paradigm for transcriptional repression and for the role of chromatin in repression. TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation. Synonyms: General transcriptional corepressor TUP1, Glucose repression regulatory protein TUP1, Flocculation suppressor protein, Repressor AER2, TUP1, AAR1, AER2, AMM1, CYC9, FLK1, SFL2, UMR7, YCR084C, YCR84.
-
UniProt
- P16649
-
途径
- Chromatin Binding
抗原
-