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APCS 抗体 (full length)

The 兔 多克隆 anti-APCS antibody is suitable to detect APCS in samples from 人. It has been validated for WB 和 IP.
产品编号 ABIN306863
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for APCS 抗体 (full length) (ABIN306863)

抗原

See all APCS 抗体
APCS (Amyloid P Component, Serum (APCS))

适用

  • 84
  • 17
  • 11
  • 2
  • 1

宿主

  • 65
  • 32
  • 2
  • 2

克隆类型

  • 67
  • 34
多克隆

标记

  • 60
  • 10
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APCS antibody is un-conjugated

应用范围

  • 58
  • 57
  • 36
  • 13
  • 12
  • 10
  • 8
  • 8
  • 6
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 16
    • 12
    • 10
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    Rabbit anti Human SH21A (SH2 DOMAIN-CONTAINING PROTEIN 1A) / (SAP)

    交叉反应

    产品特性

    SLAM (Signaling Lymphocyte-Activation Molecule) is a glycosylated type-I transmembrane protein which is present on the surface of B and T cells. SLAM is a high-affinity self-ligand which, when triggered, co-activated B or T lymphocyte responses and is considered to be important in bi-directional T - B cell stimulation. SAP (SLAM-Associated Protein) has been determined to be a 15 kDa protein. SAP is believed to the genetic defect which cauases X-linked Lymphoproliferative Syndrome (XLP). SAP is thought to bind to SLAM by the SH2 domain of the SAP protein. Binding of SAP to the SLAM protein blocks the binding of SHP-2 to the phosphorylated SLAM protein which causes XLP.

    纯化方法

    Ammonium Sulfate Precipitation

    免疫原

    Full-length recombinant SAP protein

    亚型

    IgG
  • 应用备注

    This antibody can be used for Western blotting (5-10 μg/mL) and immunoprecipiation. Optimal concentration should be evaluated by serial dilutions.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    APCS (Amyloid P Component, Serum (APCS))

    别名

    SAP

    背景

    SAP, DSHP, SLAM ASSOCIATED PROTEIN

    UniProt

    O60880
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