SMC2 抗体 (AA 523-768)
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北京 101111
Quick Overview for SMC2 抗体 (AA 523-768) (ABIN306862)
抗原
See all SMC2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 523-768
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交叉反应
- 人
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产品特性
- CAP-E, Structural maintenance of chromosomes protein 2, SMC-2,CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.
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纯化方法
- Protein A/G Chromatography
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免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant protein corresponding to amino acids 523-768 of human CAP-E and mouse myeloma cells.
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亚型
- IgG
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应用备注
- This antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))
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别名
- Chromosome Associated Protein-E
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UniProt
- O95347
抗原
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