S1PR4 抗体
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北京 101111
Quick Overview for S1PR4 抗体 (ABIN306801)
抗原
See all S1PR4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Human Sphingosine 1 Phosphate 4 Receptor (CT) (EDG6)
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交叉反应
- 人
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产品特性
- EDG-6 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-6 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-6 is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the EDG-6 receptor is the sphingosine 1-phosphate receptor-4 (S1P-4).
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纯化方法
- Ammonium Sulfate Precipitation
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anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 8-37), (N-Term) antibody
S1PR4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB1829 unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (Cytoplasmic Domain) antibodyS1PR4 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 301-384) antibodyS1PR4 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 1-384) antibodyS1PR4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人, 猴, 犬, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (Cytoplasmic Domain) antibodyS1PR4 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) antibodyS1PR4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人 WB 宿主: 小鼠 Monoclonal 1 unconjugated
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应用备注
- Detects EDG6 receptors at concentration of 5-10 μg/mL by Western blot using a human EDG6 receptor transfected cell line. Detects an approximately 45 kDa band in Cos cells transfected with full length human EDG6. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
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别名
- Sphingosine 1 Phosphate 4 Receptor (CT) (EDG6)
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背景
- Endothelial cell differentiation gene 6 C-terminal, Sphingosine-1-Phosphate Receptor-4 (S1P-4)
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UniProt
- O95977
抗原
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