VSX2 抗体
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北京 101111
Quick Overview for VSX2 抗体 (ABIN306798)
抗原
See all VSX2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Sheep anti Human chx 10 (Visual system homeobox 2) (CT)
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交叉反应
- 小鸡, 人, 小鼠, 大鼠
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产品特性
- Chx10 is a 46 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus, and spinal cord.
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纯化方法
- Ammonium Sulfate Precipitation
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亚型
- IgG
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应用备注
- Detects Chx10 by Western blot at 0.5 to 1 μg/mL. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Optimal concentration should be evaluated by serial dilutions. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- VSX2 (Visual System Homeobox 2 (VSX2))
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别名
- chx 10 (CT)
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背景
- Ceh-10 homeodomain-containing homolog
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分子量
- 46kDa
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UniProt
- P58304
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途径
- Dopaminergic Neurogenesis
抗原
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