SH3BP2 抗体
Quick Overview for SH3BP2 抗体 (ABIN306729)
抗原
See all SH3BP2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠
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产品特性
- Sh3bp2, SH3 domain-binding protein 2,3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLC 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66 % homologous to the human protein at the amino acid level.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Antibody developed using SH2 domain of the 3BP2 protein fused to GST.
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亚型
- IgG
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anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 452-561) antibody
SH3BP2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 432-481) antibodySH3BP2 适用: 人, 小鼠, 大鼠, 猴, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 165-301) antibodySH3BP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 1-561) antibodySH3BP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 392-561) antibodySH3BP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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别名
- 3BP2 (SH3 Binding Protein 2)
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UniProt
- Q06649
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途径
- TCR Signaling
抗原
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