CAPN1 抗体
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北京 101111
Quick Overview for CAPN1 抗体 (ABIN306692)
抗原
See all CAPN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti Human Calpain I, II (small subunit)
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交叉反应
- Cow, 人
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产品特性
- The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and μ-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, μ-calpain is active at micromolar (μM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and μcalpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
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纯化方法
- Protein A/G Chromatography
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亚型
- IgG1
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应用备注
- Use at 0.5-1 μg/mL for ELISA and western blot, 1-2 μg/mL for immunoprecipitation.
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限制
- 仅限研究用
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CAPN1 (Calpain 1 (CAPN1))
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别名
- Calpain I
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背景
- Mouse anti calpain I, II small subunit, p30
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UniProt
- P17655
抗原
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