PPP2R5D 抗体
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北京 101111
Quick Overview for PPP2R5D 抗体 (ABIN306653)
抗原
See all PPP2R5D 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Human Protein Phosphatase 2 A/B delta
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交叉反应
- Cow, 人, 小鼠, 大鼠
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产品特性
- PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, B , B and B . The B' (or B56) family consists of at least seven splice variants derived from five genes. RNA's for the two members of the B'' family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals. B is a novel isoform of the B class of PP2A regulatory subunits. It is widely expressed in rat tissues and appears to be involved in targeting PP2A to the cytosolic compartment.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Synthetic peptide conjugated to KLH derived from the N-terminus of PP2A/B delta
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亚型
- IgG
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应用备注
- Detects PP2A/B delta protein in rat testis by Western blot. Detects a 53 kDa band in rat brain, heart, lung, placenta, skeletal muscle, spleen, testis and thymus tissues lysates. Optimal concentration should be evaluated by serial dilutions. Applications: Western Blotting, Immunofluorescence
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))
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别名
- Protein Phosphatase 2 A/B delta
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背景
- Pp2A/Bd, rabbit anti protein phosphatase 2A, B subunit delta, PP2A B subunit delta
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UniProt
- Q14738, Q925E7, P56932
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途径
- PI3K-Akt Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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