PPP1CC 抗体
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北京 101111
Quick Overview for PPP1CC 抗体 (ABIN306646)
抗原
See all PPP1CC 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Sheep anti Human Protein Phosphatase 1 gamma 1
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产品特性
- A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein phosphorylation is one of the most common forms of reversible protein posttranslational modification (PTM), with up to 30 % of all proteins being phosphorylated at any given time. Protein kinases (PKs) are the effectors of phosphorylation and catalyse the transfer of a γ-phosphate from ATP to specific amino acids on proteins. Several hundred PKs exist in mammals and are classified into distinct super-families. Proteins are phosphorylated predominantly on Ser, Thr and Tyr residues, which account for 79.3, 16.9 and 3.8 % respectively of the phosphoproteome, at least in mammals. In contrast, protein phosphatases (PPs) are the primary effectors of dephosphorylation and can be grouped into three main classes based on sequence, structure and catalytic function. The largest class of PPs is the phosphoprotein phosphatase (PPP) family comprising PP1, PP2A, PP2B, PP4, PP5, PP6 and PP7, and the protein phosphatase Mg²+- or Mn²+-dependent (PPM) family, composed primarily of PP2C.
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纯化方法
- Ammonium Sulfate Precipitation
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亚型
- IgG
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应用备注
- Immunoblotting 1:500 to 1:1,000. Immunoprecipitation.
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限制
- 仅限研究用
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))
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别名
- Protein Phosphatase 1 gamma 1
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背景
- Pp1g1
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UniProt
- P36873, P37139
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途径
- Cellular Glucan Metabolic Process, Lipid Metabolism
抗原
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