PPP1CA 抗体
Quick Overview for PPP1CA 抗体 (ABIN306640)
抗原
See all PPP1CA 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- P16 INK4a
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交叉反应
- 人
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交叉反应 （详细）
- Human, other species not tested
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产品特性
- pp1a, rabbit anti protein phosphatase 1 alpha,The antibody is suitable to detect p16 in different tissues. Staining results may be cytoplasmatic or nuclear. Nuclear staining should be more specific. Human p16 INK4a (syn. CDKN2, MTS-1) protein is an inhibitor of Cyclin-Dependent-Kinases 4 and 6 (cdk4/cdk6). CDK4 is an important enzyme for the progression of the cell cycle during the G1-Phase. By it's inhibitory action p16 is an important regulator in the cell cycle. The gen encoding for p16 is deleted in many tumour cell lines. In adenocarcinoma of the cervix uteri usually p16 levels are increased. Endocervical p16-overexpression is mostly associated with "high risk" HPV-Typing. In other tumour types as squamous epithelial carcinoma in cervix uteri and head and neck carcinoma p16 expression usually is reduced.
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纯化方法
- Protein A affinity purification.
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免疫原
- Recombinant human p16 INK4a molecule,Monoclonal antibody DCS-50 is produced after immunisation of Balb/c mice with the full length recombinant p16 INK4a protein of human origin.
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亚型
- IgG
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anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (AA 2-330) antibody
PPP1CA 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (Center) antibodyPPP1CA 适用: 人, 大鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (AA 1-330) antibodyPPP1CA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) antibodyPPP1CA 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) antibodyPPP1CA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E9 unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (AA 192-330), (Catalytic Subunit) antibodyPPP1CA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (pThr320) antibodyPPP1CA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (AA 224-330) antibodyPPP1CA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (C-Term) antibodyPPP1CA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (AA 291-324), (pThr320) antibodyPPP1CA 适用: 人 WB 宿主: 兔 Polyclonal RB56571 unconjugated
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应用备注
- Pre-treatment with Unmasking Fluid C (Citrate Buffer) or Unmasking Fluid G at 96-100 degree of Celsius is recommended for paraffin sections.,IHC (C,P), IP,60 min at RT,1:10
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- Protein A affinity purified antibody lyophilized from PBS pH 7.4 with BSA and Na-Azide 0.09 % .
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
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别名
- Protein Phosphatase 1 alpha
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途径
- M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
抗原
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