LMO2 抗体
Our Local Distributor
北京 101111
Quick Overview for LMO2 抗体 (ABIN306631)
抗原
See all LMO2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
亚型
- IgG
-
-
-
-
限制
- 仅限研究用
-
-
-
- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
-
别名
- Rhombotin 2
-
背景
- Two homologues of the rhombotin gene have now been isolated. One of these, designated Rhom-2, is located on human chromosome 11 at band 11p13, where a cluster of T-cell leukemia-specific translocations occur, all translocation breakpoints at 11p13 are upstream of the Rhom-2 gene. Human and mouse Rhom-2 are highly conserved and, like rhombotin, encode two tandem cysteine-rich LIM domains. Rhom-2 mRNA is expressed in early mouse development in central nervous system, lung, kidney, liver, and spleen but only very low levels occur in thymus. The Rhom-2 gene is such a common site of chromosomal damage in T-cell tumors. Chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2) are consistent sites of chromosome translocation in T-cell leukemia, with the 11p15 target more rarely involved. Synonyms: LIM domain only protein, cysteine-rich protein TTG-2, T-cell translocation protein 2.
-
UniProt
- P25791
-
途径
- Chromatin Binding
抗原
-