NOLC1 抗体
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北京 101111
Quick Overview for NOLC1 抗体 (ABIN306630)
抗原
See all NOLC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti Human p130
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产品特性
- P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130 kDa.
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纯化方法
- Protein A/G Chromatography
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亚型
- IgG1
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应用备注
- Western Blots at 1:1000
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限制
- 仅限研究用
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))
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别名
- p130
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背景
- P130, Retinoblastoma-like protein 2, RBR-2, PRB2
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分子量
- 130kDa
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UniProt
- Q08999, Q64700, O55081
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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