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IL-33 抗体 (AA 112-270)

This anti-IL-33 antibody is a 小鼠 单克隆 antibody detecting IL-33 in WB, ELISA, ICC, IF 和 FACS. Suitable for 人.
产品编号 ABIN306451
发货至: 中国
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Room 801-803
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Quick Overview for IL-33 抗体 (AA 112-270) (ABIN306451)

抗原

See all IL-33 (IL33) 抗体
IL-33 (IL33) (Interleukin 33 (IL33))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-33 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

4E9
  • 抗原表位

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    AA 112-270

    原理

    Human IL-33 antibody

    纯化方法

    Purified

    免疫原

    Recombinant human IL-33 (112-270aa) purified from E. coli

    亚型

    IgG2b kappa
  • 应用备注

    Recommended dilution 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    IL-33 (IL33) (Interleukin 33 (IL33))

    别名

    IL-33

    背景

    Interleukin 33 (IL-33) is a 32 kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12 kDa and C-terminal fragment of 18 kDa by cleavage of caspase-1.

    NCBI登录号

    NP_254274

    途径

    Production of Molecular Mediator of Immune Response
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