Alpha, beta Synuclein (AA 119-140) 抗体
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Quick Overview for Alpha, beta Synuclein (AA 119-140) 抗体 (ABIN306414)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 119-140
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原理
- Human Synuclein-alpha/beta antibody
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纯化方法
- Purified
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免疫原
- Recombinant human a-synuclein (119-140aa) purified from E. coli
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亚型
- IgG1 kappa
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应用备注
- Recommended dilution 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Alpha, beta Synuclein
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别名
- Synuclein-alpha/beta
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背景
- Alpha-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Abeta component of amyloid plaques is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.
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NCBI登录号
- NP_000336, NP_003076
抗原
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