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Alpha, beta Synuclein (AA 119-140) 抗体

适用: 人 WB, ELISA, ICC, IF, FACS 宿主: 小鼠 Monoclonal 3B6 unconjugated
产品编号 ABIN306414
发货至: 中国
  • 抗原
    Alpha, beta Synuclein
    抗原表位
    • 1
    • 1
    • 1
    AA 119-140
    适用
    • 10
    • 9
    • 9
    • 1
    宿主
    • 8
    • 3
    小鼠
    克隆类型
    • 10
    • 1
    单克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
    免疫原
    Recombinant human a-synuclein (119-140aa) purified from E. coli
    克隆位点
    3B6
    亚型
    IgG1 kappa
  • 应用备注
    Recommended dilution 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原
    Alpha, beta Synuclein
    别名
    Synuclein-alpha/beta
    背景
    Alpha-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Abeta component of amyloid plaques is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.
    NCBI登录号
    NP_000336, NP_003076
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