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D-Dimer (Fibrin Degradation Product) 抗体

The 小鼠 单克隆 anti-D-Dimer (Fibrin Degradation Product) antibody is suitable to detect D-Dimer (Fibrin Degradation Product) in samples from 人. It has been validated for WB 和 ELISA.
产品编号 ABIN305042
发货至: 中国
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Quick Overview for D-Dimer (Fibrin Degradation Product) 抗体 (ABIN305042)

抗原

D-Dimer (Fibrin Degradation Product)

适用

  • 19
  • 1

宿主

  • 17
  • 3
小鼠

克隆类型

  • 17
  • 3
单克隆

标记

  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
非结合性

应用范围

  • 18
  • 16
  • 2
  • 1
Western Blotting (WB), ELISA

克隆位点

DD5
  • 特异性

    Recognizes human D-dimer and shows low cross-reactivity with fibrinogen (D-monomer). D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease. Can be used as the detection antibody in ELISA for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer,  pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.

    纯化方法

    Affinity purified

    免疫原

    Homogenized fibrin clot.

    亚型

    IgG2b
  • 应用备注

    Approved: ELISA, WB

    Usage: ELISA: This product may be used in an indirect ELISA or as a detection antibody in a sandwich ELISA together with clone DD1 (product code LS-C58035), for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer,  pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.WESTERN BLOT: Please note that non-reducing conditions are required for detection of the D-dimer.

    Not recommended for: IHC-P

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Short term: -20°C
    Long term: -20°C.
  • 抗原

    D-Dimer (Fibrin Degradation Product)

    别名

    Fibrin Degradation Product D-Dimer
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