TPP1 抗体 (Middle Region)
Quick Overview for TPP1 抗体 (Middle Region) (ABIN3044554)
抗原
See all TPP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 227-261, Middle Region
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原理
- Anti-TPP1 Antibody Picoband®
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序列
- CAQFLEQYFH DSDLAQFMRL FGGNFAHQAS VARVV
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TPP1 Antibody Picoband® (ABIN3044554). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human TPP1, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
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亚型
- IgG
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anti-Tripeptidyl Peptidase I (TPP1) (AA 1-320) antibody
TPP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase I (TPP1) (AA 198-562) antibodyTPP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase I (TPP1) (AA 195-304) antibodyTPP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-Tripeptidyl Peptidase I (TPP1) (AA 1-563) antibodyTPP1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Tripeptidyl Peptidase I (TPP1) (AA 1-563) antibodyTPP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase I (TPP1) antibodyTPP1 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase I (TPP1) (AA 284-563) antibodyTPP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase I (TPP1) antibodyTPP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase I (TPP1) (AA 371-480) antibodyTPP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: TPP1 tripeptidyl peptidase I". 2. Liu CG, Sleat DE, Donnelly RJ, Lobel P (Jun 1998). "Structural organization and sequence of CLN2, the defective gene in classical late infantile neuronal ceroid lipofuscinosis". Genomics 50 (2): 206-12. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TPP1 (Tripeptidyl Peptidase I (TPP1))
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别名
- TPP1
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背景
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Synonyms: Tripeptidyl-peptidase 1,TPP-1,3.4.14.9,Cell growth-inhibiting gene 1 protein,Lysosomal pepstatin-insensitive protease,LPIC,Tripeptidyl aminopeptidase,Tripeptidyl-peptidase I,TPP-I,TPP1,CLN2,GIG1, UNQ267/PRO304,
Tissue Specificity: Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.
Background: Tripeptidyl-peptidase 1, also known as Lysosomal pepstatin-insensitive protease, is an enzyme that in humans is encoded by the TPP1 gene. This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
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分子量
- 39 kDa
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基因ID
- 1200
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UniProt
- O14773
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途径
- Cell Division Cycle, ER-Nucleus Signaling
抗原
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