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SKAP1 抗体 (Middle Region)

SKAP1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044545
发货至: 中国
  • 抗原 See all SKAP1 抗体
    SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
    抗原表位
    • 14
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 163-189, Middle Region
    适用
    • 29
    • 19
    • 5
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 40
    • 4
    • 1
    克隆类型
    • 41
    • 4
    多克隆
    标记
    • 20
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SKAP1 antibody is un-conjugated
    应用范围
    • 26
    • 24
    • 12
    • 12
    • 9
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-SKAP55/SKAP1 Antibody Picoband®
    序列
    RMAPHLRRDS KKESCFELTS QDRRSYE
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-SKAP55/SKAP1 Antibody Picoband® (ABIN3044545). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human SKAP55, different from the related mouse and rat sequences by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product SKAP1 Primary Antibody
  • 应用备注
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. "Entrez Gene: SKAP1 src kinase associated phosphoprotein 1". 2. Marie-Cardine A, Bruyns E, Eckerskorn C, Kirchgessner H, Meuer SC, Schraven B (July 1997). "Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes". J Biol Chem 272 (26): 16077-80. 3. Wang H, Moon EY, Azouz A, et al. (2003). "SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates". Nat. Immunol. 4 (4): 366-74.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
    别名
    SKAP1 (SKAP1 产品)
    背景

    Synonyms: Src kinase-associated phosphoprotein 1,Src family-associated phosphoprotein 1,Src kinase-associated phosphoprotein of 55 kDa,SKAP-55,pp55,SKAP1,SCAP1, SKAP55,

    Tissue Specificity: Highly expressed in thymocytes and peripheral blood lymphocytes. Also expressed in spleen cells and testis. Present in T-cells (at protein level). .

    Background: Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene. This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.

    分子量
    60 kDa
    基因ID
    8631
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