SKAP1 抗体 (Middle Region)
Quick Overview for SKAP1 抗体 (Middle Region) (ABIN3044545)
抗原
See all SKAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 163-189, Middle Region
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原理
- Anti-SKAP55/SKAP1 Antibody Picoband®
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序列
- RMAPHLRRDS KKESCFELTS QDRRSYE
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SKAP55/SKAP1 Antibody Picoband® (ABIN3044545). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SKAP55, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG
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anti-Src Kinase Associated phosphoprotein 1 (SKAP1) (AA 1-100) antibody
SKAP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C11 unconjugated
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) (AA 1-358) antibodySKAP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) antibodySKAP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) (AA 1-355) antibodySKAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) (AA 1-354) antibodySKAP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) (AA 1-359) antibodySKAP1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) antibody (Biotin)SKAP1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) antibody (HRP)SKAP1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) antibody (FITC)SKAP1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Src Kinase Associated phosphoprotein 1 (SKAP1) (AA 38-87) antibodySKAP1 适用: 人, 大鼠, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human
Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: SKAP1 src kinase associated phosphoprotein 1". 2. Marie-Cardine A, Bruyns E, Eckerskorn C, Kirchgessner H, Meuer SC, Schraven B (July 1997). "Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes". J Biol Chem 272 (26): 16077-80. 3. Wang H, Moon EY, Azouz A, et al. (2003). "SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates". Nat. Immunol. 4 (4): 366-74. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
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别名
- SKAP1
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背景
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Synonyms: Src kinase-associated phosphoprotein 1,Src family-associated phosphoprotein 1,Src kinase-associated phosphoprotein of 55 kDa,SKAP-55,pp55,SKAP1,SCAP1, SKAP55,
Tissue Specificity: Highly expressed in thymocytes and peripheral blood lymphocytes. Also expressed in spleen cells and testis. Present in T-cells (at protein level). .
Background: Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene. This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
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分子量
- 60 kDa
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基因ID
- 8631
抗原
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