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RNH1 抗体 (N-Term)

This anti-RNH1 antibody is a 兔 多克隆 antibody detecting RNH1 in WB, IHC, FACS 和 ICC. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN3044540
发货至: 中国

Quick Overview for RNH1 抗体 (N-Term) (ABIN3044540)

抗原

See all RNH1 抗体
RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

  • 50
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多克隆

标记

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This RNH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
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    AA 2-37, N-Term

    原理

    Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband®

    序列

    SLDIQSLDIQ CEELSDARWA ELLPLLQQCQ VVRLDD

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (ABIN3044540). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
    Immunocytochemistry, 0.5-1 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    1. "Entrez Gene: RNH1 ribonuclease/angiogenin inhibitor 1". 2. Weremowicz S, Fox EA, Morton CC, Vallee BL (1991). "The placental ribonuclease inhibitor (RNH) gene is located on chromosome subband 11p15.5.". Genomics 8(4): 717-21. 3. Zneimer SM, Crawford D, Schneider NR, Beutler B (1991). "Mapping of the human ribonuclease inhibitor gene (RNH) to chromosome 11p15 by in situ hybridization.". Genomics 8 (1): 175-8.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

    别名

    RNH1

    背景

    Synonyms: Ribonuclease inhibitor,Placental ribonuclease inhibitor,Placental RNase inhibitor,Ribonuclease/angiogenin inhibitor 1,RAI,RNH1,PRI, RNH,

    Tissue Specificity: Widely expressed, high expression found in skeletal muscle. .

    Background: Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

    分子量

    50 kDa

    基因ID

    6050

    UniProt

    P13489
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