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Filaggrin 抗体 (AA 1-261)

This anti-Filaggrin antibody is a 兔多克隆 antibody detecting Filaggrin in IHC 和 WB. Suitable for 人.

Western blot analysis of Filaggrin expression in 22RV1 whole cell lysates (lane 1). (Filaggrin 抗体 (AA 1-261))

Filaggrin was detected in paraffin-embedded sections of human Tonsil tissues using rabbit anti- Filaggrin Antigen Affinity purified polyclonal antibody at 1 μg/mL. (Filaggrin 抗体 (AA 1-261))

2 images

产品编号 ABIN3044525

发货至: 中国

Quick Overview for Filaggrin 抗体 (AA 1-261) (ABIN3044525)

抗原

See all Filaggrin (FLG) 抗体

Filaggrin (FLG)

适用

人

宿主

兔

克隆类型

多克隆

标记

57
15
9
6
5
5
5
5
5
5
2
1
1
1
1
1
1

This Filaggrin antibody is un-conjugated

应用范围

87
47
42
28
22
19
15
13
8
8
5
4
3
1
1
1

Immunohistochemistry (IHC), Western Blotting (WB)

Discover our top product FLG Primary Antibody

抗原表位
38

31

8

6

4

4

3

2

2

1

1

1

1

1

1

1

1

1

1
AA 1-261

原理

Anti-Filaggrin/FLG Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Filaggrin/FLG Antibody Picoband® (ABIN3044525). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human Filaggrin recombinant protein (Position: M1-R261).

亚型

IgG
anti-Filaggrin (FLG) (AA 119-336) antibody
FLG 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (AA 998-1104) antibody
FLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1563 unconjugated

anti-Filaggrin (FLG) (AA 198-288) antibody
FLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1561 unconjugated

anti-Filaggrin (FLG) (AA 3838-4061) antibody
FLG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (AA 198-288) antibody
FLG 适用: 人 IHC, ISt, StM 宿主: 兔 Monoclonal FLG-1957R unconjugated Recombinant Antibody

anti-Filaggrin (FLG) (AA 198-288) antibody
FLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal rFLG-1561 unconjugated Recombinant Antibody

anti-Filaggrin (FLG) antibody
FLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (AA 3905-4031) antibody
FLG 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (pTyr654) antibody
FLG 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (pTyr154) antibody
FLG 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Kypriotou, Magdalini, Huber, Marcel, Hohl, Daniel (September 2012)."The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the 'fused genes' family". Experimental Dermatology 21 (9): 643-649. 2. Markova, NG, Marekov, LN, Chipev, CC, Gan, SQ, Idler, WW, Steinert, PM (January 1993). "Profilaggrin is a major epidermal calcium-binding protein.". Molecular and Cellular Biology 13 (1): 613-25.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

Filaggrin (FLG)

别名

FLG

背景

Synonyms: Filaggrin,FLG,
Tissue Specificity: Expressed in skin, thymus, stomach, tonsils, testis, placenta, kidney, pancreas, mammary gland, bladder, thyroid, salivary gland and trachea, but not detected in heart, brain, liver, lung, bone marrow, small intestine, spleen, prostate, colon, or adrenal gland (PubMed:19384417). In the skin, mainly expressed in stratum granulosum of the epidermis (PubMed:1429717) (PubMed:19384417). .
Background: In humans, profillagrin is encoded by the?FLG?gene, which is part of the S100 fused-type protein (SFTP) family within the?epidermal differentiation complex?on?chromosome 1q21. The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.

分子量

435 kDa

基因ID

2312

UniProt

P20930

途径

Sensory Perception of Sound, Stem Cell Maintenance

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