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Fatty Acid Synthase 抗体 (AA 1-226)

Name: Fatty Acid Synthase 抗体 (AA 1-226)
SKU: ABIN3044520
Availability: OutOfStock

FASN 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of FASN expression in HEPG2 whole cell lysates (lane 1), U87 whole cell lysates (lane 2) and RAJI whole cell lysates (lane 3). (Fatty Acid Synthase 抗体 (AA 1-226))

IHC analysis of FASN using anti-FASN antibody . (Fatty Acid Synthase 抗体 (AA 1-226))

IHC

FASN was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti- FASN Antigen Affinity purified polyclonal antibody at 1 μg/mL. (Fatty Acid Synthase 抗体 (AA 1-226))

IHC (p)

IHC

4 images

(1 reference)

产品编号 ABIN3044520

发货至: 中国

Datasheet as PDF

抗原 See all Fatty Acid Synthase (FASN) 抗体

Fatty Acid Synthase (FASN)
抗原表位
6

6

5

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-226
适用
73

37

29

5

3

2

2

2

1

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
64

21

2
兔
Compatible Secondaries
克隆类型
56

31
多克隆
标记
69

3

2

2

2

2

2

2

2

1
This Fatty Acid Synthase antibody is un-conjugated
应用范围
62

36

34

29

26

21

14

6

3

2

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

原理

Anti-Fatty Acid Synthase/FASN Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Fatty Acid Synthase/FASN Antibody Picoband® (ABIN3044520). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3% and 90.7% amino acid (aa) sequence identity with mouse and rat FASN, respectively.

亚型

IgG

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anti-Fatty Acid Synthase (FASN) (N-Term) antibody
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anti-Fatty Acid Synthase (FASN) antibody
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FASN 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 497CT15-2-5 unconjugated

anti-Fatty Acid Synthase (FASN) (AA 942-973) antibody
FASN 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17743 unconjugated

anti-Fatty Acid Synthase (FASN) (AA 942-973) antibody
FASN 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fatty Acid Synthase (FASN) (AA 2243-2505) antibody
FASN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fatty Acid Synthase (FASN) (AA 651-750) antibody
FASN 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Fatty Acid Synthase (FASN) (AA 2155-2495) antibody
FASN 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Immunofluorescence, 5 μg/mL
1. "Entrez Gene: FASN fatty acid synthase". 2. Jayakumar A, Tai MH, Huang WY, al-Feel W, Hsu M, Abu-Elheiga L, Chirala SS, Wakil SJ (Oct 1995). "Human fatty acid synthase: properties and molecular cloning". Proc Natl Acad Sci U S A 92 (19): 8695-9. 3. Smith S, Witkowski A, Joshi AK (July 2003). "Structural and functional organization of the animal fatty acid synthase". Prog. Lipid Res. 42 (4): 289-317.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Lu, Ma, Cai: "Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis." in: Tumour biology, Vol. 39, Issue 4, pp. 1010428317697570, (2017) (PubMed).
抗原

Fatty Acid Synthase (FASN)

别名

FASN (FASN 产品)

背景

Synonyms: Fatty acid synthase;2.3.1.85;[Acyl-carrier-protein] S-acetyltransferase;2.3.1.38;[Acyl-carrier-protein] S-malonyltransferase;2.3.1.39;3-oxoacyl-[acyl-carrier-protein] synthase;2.3.1.41;3-oxoacyl-[acyl-carrier-protein] reductase;1.1.1.100;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;4.2.1.59;Enoyl-[acyl-carrier-protein] reductase;1.3.1.39;Oleoyl-[acyl-carrier-protein] hydrolase;3.1.2.14;FASN;FAS;
Tissue Specificity: Ubiquitous. Prominent expression in brain, lung, and liver. .
Background: Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. It is mapped to 17q25. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

分子量

273 kDa

基因ID

2194

UniProt

P49327

途径

AMPK Signaling