Fatty Acid Synthase 抗体 (AA 1-226)
(1 reference)Quick Overview for Fatty Acid Synthase 抗体 (AA 1-226) (ABIN3044520)
抗原
See all Fatty Acid Synthase (FASN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-226
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原理
- Anti-Fatty Acid Synthase/FASN Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Fatty Acid Synthase/FASN Antibody Picoband® (ABIN3044520). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3% and 90.7% amino acid (aa) sequence identity with mouse and rat FASN, respectively.
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亚型
- IgG
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anti-Fatty Acid Synthase (FASN) (AA 1-439) antibody
FASN 适用: 人 WB, IP, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F2-1F3 unconjugated
anti-Fatty Acid Synthase (FASN) (AA 2212-2511) antibodyFASN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Synthase (FASN) (N-Term) antibodyKO Validated FASN 适用: 人 WB, IP, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Synthase (FASN) antibodyFASN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-Fatty Acid Synthase (FASN) (AA 942-973) antibodyFASN 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 497CT15-2-5 unconjugated
anti-Fatty Acid Synthase (FASN) (AA 942-973) antibodyFASN 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17743 unconjugated
anti-Fatty Acid Synthase (FASN) (AA 942-973) antibodyFASN 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Synthase (FASN) (AA 2243-2505) antibodyFASN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Synthase (FASN) (AA 651-750) antibodyFASN 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Synthase (FASN) (AA 2155-2495) antibodyFASN 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Immunofluorescence, 5 μg/mL
1. "Entrez Gene: FASN fatty acid synthase". 2. Jayakumar A, Tai MH, Huang WY, al-Feel W, Hsu M, Abu-Elheiga L, Chirala SS, Wakil SJ (Oct 1995). "Human fatty acid synthase: properties and molecular cloning". Proc Natl Acad Sci U S A 92 (19): 8695-9. 3. Smith S, Witkowski A, Joshi AK (July 2003). "Structural and functional organization of the animal fatty acid synthase". Prog. Lipid Res. 42 (4): 289-317. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis." in: Tumour biology, Vol. 39, Issue 4, pp. 1010428317697570, (2017) (PubMed).
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: "Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis." in: Tumour biology, Vol. 39, Issue 4, pp. 1010428317697570, (2017) (PubMed).
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- Fatty Acid Synthase (FASN)
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别名
- FASN
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背景
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Synonyms: Fatty acid synthase;2.3.1.85;[Acyl-carrier-protein] S-acetyltransferase;2.3.1.38;[Acyl-carrier-protein] S-malonyltransferase;2.3.1.39;3-oxoacyl-[acyl-carrier-protein] synthase;2.3.1.41;3-oxoacyl-[acyl-carrier-protein] reductase;1.1.1.100;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;4.2.1.59;Enoyl-[acyl-carrier-protein] reductase;1.3.1.39;Oleoyl-[acyl-carrier-protein] hydrolase;3.1.2.14;FASN;FAS;
Tissue Specificity: Ubiquitous. Prominent expression in brain, lung, and liver. .
Background: Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. It is mapped to 17q25. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
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分子量
- 273 kDa
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基因ID
- 2194
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UniProt
- P49327
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途径
- AMPK Signaling
抗原
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