CXCL5 抗体 (AA 38-130)
Quick Overview for CXCL5 抗体 (AA 38-130) (ABIN3044514)
抗原
See all CXCL5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 38-130
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原理
- Anti-CXCL5 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CXCL5 Antibody Picoband® (ABIN3044514). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7% and 76.3% amino acid (aa) sequence identity with human and mouse CXCL5, respectively.
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亚型
- IgG
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应用备注
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ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Rat
1. "Entrez Gene: CXCL5 chemokine (C-X-C motif) ligand 5". 2. Chang MS, McNinch J, Basu R, Simonet S (Nov 1994). "Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene". J Biol Chem 269 (41): 25277-82. 3. Persson T, Monsef N, Andersson P, Bjartell A, Malm J, Calafat J, Egesten A (2003). "Expression of the neutrophil-activating CXC chemokine ENA-78/CXCL5 by human eosinophils". Clin. Exp. Allergy 33 (4): 531-7. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
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别名
- Cxcl5
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背景
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Synonyms: C-X-C motif chemokine 5,Cytokine LIX,Small-inducible cytokine B5,Cxcl5,Scyb5,
Tissue Specificity: At least expressed in the lung and trachea.
Background: C-X-C motif chemokine 5?or ENA-78 is a?protein?that in humans is encoded by the?CXCL5?gene. The protein encoded by this gene, CXCL5 is a small?cytokine?belonging to the CXC?chemokine?family. It is produced following stimulation of cells with the inflammatory cytokines?interleukin-1?or?tumor necrosis factor-alpha.?Expression of CXCL5 has also been observed ineosinophils, and can be inhibited with the type II?interferon?IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possessing?angiogenic?properties. It elicits these effects by interacting with the cell surface?chemokine receptor?CXCR2.?The?gene?for CXCL5 is encoded on four?exons?and is located on human?chromosome 4?amongst several other CXC chemokine genes.?CXCL5 has been implicated in connective tissue remodelling.?Also, CXCL5 has been described to regulate neutrophil homeostasis.
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分子量
- 14 kDa
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基因ID
- 105988538
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UniProt
- P97885
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
抗原
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