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Ceruloplasmin 抗体 (AA 20-258)

This anti-Ceruloplasmin antibody is a 兔 多克隆 antibody detecting Ceruloplasmin in WB 和 IHC. Suitable for 大鼠 和 小鼠.
产品编号 ABIN3044508
发货至: 中国

Quick Overview for Ceruloplasmin 抗体 (AA 20-258) (ABIN3044508)

抗原

See all Ceruloplasmin (CP) 抗体
Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

适用

  • 62
  • 13
  • 10
大鼠, 小鼠

宿主

  • 51
  • 16
  • 6
  • 3
  • 1

克隆类型

  • 59
  • 16
多克隆

标记

  • 48
  • 12
  • 7
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  • 2
  • 2
This Ceruloplasmin antibody is un-conjugated

应用范围

  • 54
  • 40
  • 31
  • 22
  • 14
  • 14
  • 11
  • 8
  • 7
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-258

    原理

    Anti-Ceruloplasmin/CP Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Rabbit IgG polyclonal antibody for Ceruloplasmin(CP) detection. Tested with WB, IHC-P in Mouse,Rat.
    Gene Name: ceruloplasmin (ferroxidase)
    Protein Name: Ceruloplasmin

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse Ceruloplasmin recombinant protein (Position: R20-M258). Mouse Ceruloplasmin shares 80.8% and 91.2% amino acid (aa) sequence identity with human and rat Ceruloplasmin, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
    1. Koschinsky ML, Funk WD, van Oost BA, MacGillivray RT (Jul 1986)."Complete cDNA sequence of human preceruloplasmin". Proceedings of the National Academy of Sciences of the United States of America 83 (14): 5086-90. 2. Royle NJ, Irwin DM, Koschinsky ML, MacGillivray RT, Hamerton JL (May 1987). "Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively". Somatic Cell and Molecular Genetics 13(3): 285-92. 3. Takahashi N, Ortel TL, Putnam FW (Jan 1984). "Single-chain structure of human ceruloplasmin: the complete amino acid sequence of the whole molecule". Proceedings of the National Academy of Sciences of the United States of America 81 (2): 390-4.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

    别名

    Cp

    背景

    Synonyms: Ceruloplasmin;1.16.3.1;Ferroxidase;Cp;

    Tissue Specificity: Expressed in many tissues, including liver, eye and brain. .

    Background: Ceruloplasmin  (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II)transferrin to Fe (III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

    分子量

    130 kDa

    基因ID

    12870

    UniProt

    Q61147

    途径

    Transition Metal Ion Homeostasis
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