SCG3 抗体 (C-Term)
Quick Overview for SCG3 抗体 (C-Term) (ABIN3044496)
抗原
See all SCG3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 438-450, C-Term
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原理
- Anti-Secretogranin 3/SCG3 Antibody Picoband®
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序列
- DFINKQADAY VEK
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Secretogranin 3/SCG3 Antibody (ABIN3044496). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Secretogranin 3, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Secretogranin III (SCG3) (AA 20-468) antibody
SCG3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (AA 199-468) antibodySCG3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (N-Term) antibodySCG3 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (Internal Region) antibodySCG3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (C-Term) antibodySCG3 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (C-Term) antibodySCG3 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (N-Term) antibodySCG3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (AA 205-432) antibodySCG3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (C-Term) antibodySCG3 适用: 人, 小鼠, 马, 兔, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Secretogranin III (SCG3) (AA 337-386) antibodySCG3 适用: 人, 大鼠, 马, Cow, 犬, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunocytochemistry , 0.5-1 μg/mL, Human, -
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, Rat, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Related Articles, LinksTanabe A, Yanagiya T, Iida A, Saito S, Sekine A, Takahashi A, Nakamura T, Tsunoda T, Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K, Shimada T, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K.Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.J Clin Endocrinol Metab. 2007 Mar,92(3):1145-54. Epub 2007 Jan 2. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SCG3 (Secretogranin III (SCG3))
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别名
- SCG3
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背景
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Synonyms: Secretogranin-3,Secretogranin III,SgIII,SCG3,UNQ2502/PRO5990,
Tissue Specificity: Expressed in brain, heart, kidney, liver and skeletal muscle. .
Background: SCG3 (secretogranin III) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion. SCG3 was the only gene within a haplotype block that contained rs3764220. SCG3 mRNA and immunoreactivity were detected in the paraventricular nucleus, lateral hypothalamic area, and arcuate nucleus, and the protein coexisted with orexin, melanin-concentrating hormone, neuropeptide Y, and proopiomelanocortin. SCG3 formed a granule-like structure together with these neuropeptides.
Sequence Similarities: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
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分子量
- 62-65 kDa
抗原
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