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- 抗原 See all DLG4 抗体
- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
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抗原表位
- AA 492-507, C-Term
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适用
- 大鼠, 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DLG4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Disks large homolog 4(DLG4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- RRVERREWSR LKAKDW
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Disks large homolog 4(DLG4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: discs, large homolog 4(Drosophila)
Protein Name: Disks large homolog 4 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PSD95(492-507aa RRVERREWSRLKAKDW), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product DLG4 Primary Antibody
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anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA, mIHC 宿主: 小鼠 Monoclonal 6G6 unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (C-Term) antibodyDLG4 适用: 大鼠, 小鼠, 人 WB, IHC, ELISA, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibodyDLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (HRP)DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 HRP
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (FITC)DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 FITC
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Alkaline Phosphatase (AP))DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 Alkaline Phosphatase (AP)
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Biotin)DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 Biotin
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PE)DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 PE
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (APC)DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 APC
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PerCP)DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 PerCP
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
- 别名
- DLG4 (DLG4 产品)
- 别名
- 11 antibody, CG1725 antibody, CG1730 antibody, CPD antibody, DLG antibody, DLG-A antibody, Discs-large antibody, Dlg antibody, Dlg-A antibody, Dlg1 antibody, DlgA antibody, Dmel\\CG1725 antibody, Drodlg antibody, PSD95 antibody, SAP97 antibody, anon-EST:Posey93 antibody, anon-WO03040301.258 antibody, anon-WO03040301.260 antibody, anon-WO03040301.268 antibody, d. lg.-1 antibody, dlg antibody, dlg-1 antibody, dlg-A antibody, dlgA antibody, dlgS97 antibody, l(1)10Bf antibody, l(1)G0276 antibody, l(1)G0342 antibody, l(1)G0456 antibody, l(1)G19 antibody, l(1)L11 antibody, l(1)bwn antibody, l(1)d.lg-1 antibody, l(1)d.lg.-1 antibody, l(1)discs large antibody, l(1)dlg antibody, l(1)dlg-1 antibody, l(1)dlg1 antibody, l(1)l.pr.-2 antibody, l(1)lpr-2 antibody, misb antibody, dlgh4 antibody, psd95 antibody, sap90 antibody, sap-90 antibody, LLGL1 antibody, Dlgh4 antibody, PSD-95 antibody, SAP90 antibody, SAP90A antibody, Sap90 antibody, SAP-90 antibody, DLG4 antibody, discs large 1 antibody, discs, large homolog 4 antibody, discs large MAGUK scaffold protein 4 antibody, discs, large homolog 4b (Drosophila) antibody, discs, large homolog 4 (Drosophila) antibody, dlg1 antibody, dlg4 antibody, DLG4 antibody, dlg4b antibody, Dlg4 antibody
- 背景
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DLG4 discs large homolog 4, also known as PSD95 or SAP-90, is a protein that in humans is encoded by the DLG4 gene. It is a member of the membrane-associated guanylate kinase(MAGUK) family. This gene is mapped to 17p13.1. DLG4 can heteromultimerize with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Overexpression of DLG4 in hippocampal neurons could drive maturation of glutamatergic synapses. DLG4 can orchestrate synaptic development and it has a role in synapse stabilization and plasticity. Ubiquitination of DLG4 through an MDM2-mediated pathway can regulate AMPA receptor surface expression during synaptic plasticity.
Synonyms: Discs large homolog 4 antibody|Disks large homolog 4 antibody|DLG 4 antibody|DLG4 antibody|DLG4_HUMAN antibody|FLJ97752 antibody|FLJ98574 antibody|Human post synaptic density protein 95 antibody|Human post-synaptic density protein 95 antibody|Post synaptic density protein 95 antibody|Postsynaptic density protein 95 antibody|PSD 95 antibody|PSD-95 antibody|PSD95 antibody|SAP 90 antibody|SAP-90 antibody|SAP90 antibody|Synapse associated protein 90 antibody|Synapse-associated protein 90 antibody|Tax interaction protein 15 antibody - UniProt
- P78352
- 途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
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