SOX2 抗体 (Middle Region)
(2 references)Our Local Distributor
北京 101111
Quick Overview for SOX2 抗体 (Middle Region) (ABIN3044477)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- Anti-Transcription factor SOX-2 SOX2 Antibody
-
序列
- YSMMQDQLGY PQH
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
预测反应
- different from the related mouse,rat sequence by one amino acid.
-
产品特性
- Anti-Transcription factor SOX-2 SOX2 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SOX2, different from the related mouse and rat sequence by one amino acid.
-
亚型
- IgG
-
-
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
KO Validated SOX2 适用: 人 WB, IF, FACS, ICC, IHC (p), IP, IHC (fro), CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 227-317) antibodySOX2 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibodySOX2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal SOX2-1791 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119), (N-Term) antibodySOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14026 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibodySOX2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibodySOX2 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 10F10 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibodySOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, Pig, 绵羊, 斑马鱼, 犬, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (C-Term) antibodySOX2 适用: 人, 小鼠 WB, IF, ICC, ChIP-seq, ChIP, CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 251-284) antibodySOX2 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB14259 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibodyVerified SOX2 适用: 人 WB, IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
- Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, RatWestern blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
-
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
-
: "Derivation and Identification of Motor Neurons from Human Urine-Derived Induced Pluripotent Stem Cells." in: Stem cells international, Vol. 2018, pp. 3628578, (2018) (PubMed).
: "MicroRNA-184 inhibits cell proliferation and invasion, and specifically targets TNFAIP2 in Glioma." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 27, (2015) (PubMed).
-
-
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
-
别名
- SOX2
-
背景
-
Background: SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency of undifferentiated embryonic stem cells. Sox2 is a member of the Sox family of transcription factors, which have been shown to play key roles in many stages of mammalian development. This gene is mapped to 3q26.33. It is found that SOX2 can regulate OCT3/4 expression and maintains ES pluripotency through upstream transcription factors. SOX2 is identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinoma. In addition to those, SOX2 has a critical role in maintenance of embryonic and neural stem cells and holds great promise in research involving induced pluripotency, an emerging and very promising field of regenerative medicine.
Gene Full Name: SRY-box transcription factor 2
Sequence Similarities: Contains 1 HMG box DNA-binding domain.
-
分子量
- 36 kDa
-
基因ID
- 6657
-
UniProt
- P48431
-
途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
-
