(1 reference)-
- 抗原 See all HMMR 抗体
- HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))
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抗原表位
- AA 706-724, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HMMR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-CD168/HMMR Antibody Picoband®
- 序列
- KEGNTNCYRA PMECQESWK
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-/HMMR Antibody (ABIN3044455). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CD168.
- 亚型
- IgG
- Top Product
- Discover our top product HMMR Primary Antibody
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anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 306-497) antibody
HMMR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2F2C9 unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 51-150) antibodyHMMR 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 280-340) antibodyHMMR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 577-724) antibodyHMMR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) antibodyHMMR 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 1-300) antibodyHMMR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 668-697), (C-Term) antibodyHMMR 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17647 unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 478-653) antibodyHMMR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 675-705), (C-Term) antibodyHMMR 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) antibodyHMMR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Entwistle, J., Zhang, S., Yang, B., Wong, C., Li, Q., Hall, C. L., Jingbo, A., Mowat, M., Greenberg, A. H., Turley, E. A.Characterization of the murine gene encoding the hyaluronan receptor RHAMM.Gene 163: 233-238, 1995. 2. Hall, C., Yang, B., Yang, X., Zhang, S., Turley, M., Samuel, S., Lange, L. A., Wang, C., Curpen, G. D., Savani, R. C., Greenberg, A. H., Turley, E. A.Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformation.Cell 82: 19-28, 1995. 3. Savani, R. C., Wang, C., Yang, B. H., Zhang, S. W., Kinsella, M. G., Wight, T. N., Stern, R., Nance, D. M., Turley, E. A.Migration of bovine aortic smooth muscle cells after wounding injury: the role of hyaluronan and RHAMM.J. Clin. Invest. 95: 1158-1168, 1995. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
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: "RHAMM Expression in the Rat Endometrium during the Estrous Cycle and following Implantation." in: Journal of reproduction & infertility, Vol. 13, Issue 3, pp. 131-7, (2013) (PubMed).
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: "RHAMM Expression in the Rat Endometrium during the Estrous Cycle and following Implantation." in: Journal of reproduction & infertility, Vol. 13, Issue 3, pp. 131-7, (2013) (PubMed).
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- 抗原
- HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))
- 别名
- HMMR (HMMR 产品)
- 背景
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Synonyms: Hyaluronan mediated motility receptor,Intracellular hyaluronic acid-binding protein,Receptor for hyaluronan-mediated motility,CD168,HMMR,IHABP, RHAMM,
Background: HMMR, Hyaluronan-mediated motility receptor, is a protein which in humans is encoded by the HMMR gene. RHAMM was originally discovered as a soluble protein that altered migratory cell behavior and bound to hyaluronan, HMMR is less well studied than the main hyaluronan (HA) receptor, CD44. In contrast to CD44 and other cell-surface receptors which contain the classical membrane spanning domain and signal sequence for secretion from the endoplasmic reticulum/Golgi complex, HMMR does not contain a membrane spanning domain nor does the mRNA transcript contain a signal sequence. HMMR normally is localized inside the cell and is only release by certain, poorly defined stimuli. The transport of HMMR to the extracellular space still is unclear but may involve transport channels or proteins, flippase activity, or exocytosis. Intracellularly, HMMR associates with microtubules and, working with BRCA1 and BARD1, plays a role in the regulation of mitosis. Extracellularly, HMMR associates with CD44, and upon binding to HA, activates intracellular signaling pathways. Variants of HMMR caused by alternative splicing have been observed, but not thoroughly studied.
- 分子量
- 84 kDa
- UniProt
- O75330
- 途径
- Glycosaminoglycan Metabolic Process
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