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DRD3 抗体 (C-Term)

This 兔 多克隆 anti-DRD3 antibody specifically detects DRD3 in WB 和 IHC. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN3044448
发货至: 中国
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Quick Overview for DRD3 抗体 (C-Term) (ABIN3044448)

抗原

See all DRD3 抗体
DRD3 (Dopamine Receptor D3 (DRD3))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This DRD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    AA 352-367, C-Term

    原理

    Anti-Dopamine Receptor D3/DRD3 Antibody

    序列

    NTHCQTCHVS PELYSA

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Dopamine Receptor D3/DRD3 Antibody (ABIN3044448). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine Receptor D3, different from the related rat and mouse sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DRD3 (Dopamine Receptor D3 (DRD3))

    别名

    DRD3

    背景

    Synonyms: D (3) dopamine receptor,Dopamine D3 receptor,DRD3,

    Tissue Specificity: Brain.

    Background: DRD3 is a dopamine receptor that differs in its pharmacology and signaling system from the D1 and D2 receptors and represents both an autoreceptor and a postsynaptic receptor. DRD3 is localized to limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. The DRD3 gene, which is mapped to chromosome 3, is like the DRD2 gene but unlike most other members of this superfamily and it contains introns, 5 in number. The position of 2 of the introns corresponds to that of introns in DRD2. The D3 receptor appeared to mediate some of the effects of antipsychotic drugs and drugs used in the treatment of Parkinson disease, which were previously though to interact only with D2 receptors.

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

    分子量

    59 kDa

    UniProt

    P35462

    途径

    Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity
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