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GABRA1 抗体 (C-Term)

Cited in 1 publication. The 兔 多克隆 anti-GABRA1 antibody (ABIN3044445) specifically detects GABRA1 in WB 和 IHC. The antibody is reactive with 大鼠, 人 和 小鼠 samples.
产品编号 ABIN3044445
发货至: 中国
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Quick Overview for GABRA1 抗体 (C-Term) (ABIN3044445)

抗原

See all GABRA1 抗体
GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

适用

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大鼠, 人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GABRA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    C-Term

    原理

    Anti-GABA A Receptor alpha 1/GABRA1 Antibody

    序列

    ATYLNREPQL KAPTPHQ

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    产品特性

    Anti-GABA A Receptor alpha 1/GABRA1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human GABA A Receptor alpha 1, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, MouseWestern blot, 0.1-0.5 μg/mL, Human, Rat, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Bao, Wang, Wei, Wang, Wuyun, Bo: "Role of microRNA-4458 in patients with non-small-cell lung cancer." in: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).

  • 抗原

    GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

    别名

    GABRA1

    背景

    Background: GABRA1, Gamma-aminobutyric acid receptor subunit alpha-1, is a protein that in humans is encoded by the GABRA1 gene. The 1,055-bp GABRA1 clone contained an open reading frame and 260 nucleotides in the 5-prime noncoding region. The 351-amino acid sequence shows 97 % homology with its bovine counterpart. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

    Gene Full Name: gamma-aminobutyric acid type A receptor subunit alpha1

    Sequence Similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.

    分子量

    52 kDa

    基因ID

    2554

    UniProt

    P14867
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