EPHA1 抗体 (C-Term)
Quick Overview for EPHA1 抗体 (C-Term) (ABIN3044443)
抗原
See all EPHA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 963-976, C-Term
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原理
- Anti-Eph receptor A1/EPHA1 Antibody Picoband®
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序列
- HQKRILCSIQ GFKD
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Eph receptor A1/EPHA1 Antibody (ABIN3044443). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Eph receptor A1, identical to the related rat and mouse sequences.
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亚型
- IgG
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Hattori, M., Osterfield, M., Flanagan, J. G.Regulated cleavage of a contact-mediated axon repellent.Science 289: 1360-1365, 2000. 2. Torii, M., Hashimoto-Torii, K., Levitt, P., Rakic, P.Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling.Nature 461: 524-528, 2009. Note: Erratum: Nature 462: 674 only, 2009. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
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别名
- EPHA1
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背景
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Synonyms: Ephrin type-A receptor 1,hEpha1,2.7.10.1,EPH tyrosine kinase,EPH tyrosine kinase 1,Erythropoietin-producing hepatoma receptor,Tyrosine-protein kinase receptor EPH,EPHA1,EPH, EPHT, EPHT1,
Tissue Specificity: Overexpressed in several carcinomas.
Background: EPHA1, EPH receptor A1, is a protein that in humans is encoded by the EPHA1 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The EPHA1 gene is mapped to 7q34-q35. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
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分子量
- 113 kDa
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UniProt
- P21709
抗原
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