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EPHA1 抗体 (C-Term)

This anti-EPHA1 antibody is a 兔 多克隆 antibody detecting EPHA1 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3044443
发货至: 中国

Quick Overview for EPHA1 抗体 (C-Term) (ABIN3044443)

抗原

See all EPHA1 抗体
EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

适用

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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 101
  • 9

克隆类型

  • 102
  • 9
多克隆

标记

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  • 1
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This EPHA1 antibody is un-conjugated

应用范围

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  • 38
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  • 3
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 9
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 963-976, C-Term

    原理

    Anti-Eph receptor A1/EPHA1 Antibody Picoband®

    序列

    HQKRILCSIQ GFKD

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Eph receptor A1/EPHA1 Antibody (ABIN3044443). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Eph receptor A1, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Hattori, M., Osterfield, M., Flanagan, J. G.Regulated cleavage of a contact-mediated axon repellent.Science 289: 1360-1365, 2000. 2. Torii, M., Hashimoto-Torii, K., Levitt, P., Rakic, P.Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling.Nature 461: 524-528, 2009. Note: Erratum: Nature 462: 674 only, 2009.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

    别名

    EPHA1

    背景

    Synonyms: Ephrin type-A receptor 1,hEpha1,2.7.10.1,EPH tyrosine kinase,EPH tyrosine kinase 1,Erythropoietin-producing hepatoma receptor,Tyrosine-protein kinase receptor EPH,EPHA1,EPH, EPHT, EPHT1,

    Tissue Specificity: Overexpressed in several carcinomas.

    Background: EPHA1, EPH receptor A1, is a protein that in humans is encoded by the EPHA1 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The EPHA1 gene is mapped to 7q34-q35. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.

    Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.

    分子量

    113 kDa

    UniProt

    P21709
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