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Dopamine Receptor d1 抗体 (Middle Region)

DRD1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044442
发货至: 中国
  • 抗原 See all Dopamine Receptor d1 (DRD1) 抗体
    Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
    抗原表位
    • 16
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    • 2
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    AA 221-242, Middle Region
    适用
    • 77
    • 64
    • 43
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 83
    • 4
    • 1
    克隆类型
    • 75
    • 12
    多克隆
    标记
    • 33
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    This Dopamine Receptor d1 antibody is un-conjugated
    应用范围
    • 66
    • 32
    • 27
    • 26
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    • 25
    • 16
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    • 14
    • 8
    • 8
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for D(1A) dopamine receptor(DRD1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    AQKQIRRIAA LERAAVHAKN CQ
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for D(1A) dopamine receptor(DRD1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: dopamine receptor D1
    Protein Name: D(1A) dopamine receptor
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human DRD1 (221-242aa AQKQIRRIAALERAAVHAKNCQ), different from the related rat and mouse sequences by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product DRD1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
    别名
    DRD1 (DRD1 产品)
    别名
    DRD1 antibody, Dop1 antibody, D1A antibody, DADR antibody, DRD1A antibody, drd1 antibody, C030036C15Rik antibody, Drd-1 antibody, Drd1 antibody, Gpcr15 antibody, D1a antibody, Drd1a antibody, dopamine receptor D1 antibody, dopamine receptor, D1 antibody, dopamine receptor D1b antibody, DRD1 antibody, Dop1 antibody, drd1b antibody, Drd1 antibody
    背景
    Dopamine receptor D1, also known as DRD1, is a human gene. It is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G(or guanine nucleotide-binding) proteins. D2 receptors inhibit adenylyl cyclase, but D1 receptors stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. Dopamine D1 and D2 receptors are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1 receptors regulate neuron growth and differentiation, influence behaviour and modify dopamine D2 receptor-mediated events. And the presence of a D1 receptor gene restriction fragment length polymorphism will be helpful for future disease linkage studies. DRD1 also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.

    Synonyms: D(1A) dopamine receptor antibody|D1A dopamine receptor antibody|DADR antibody|Dopamine D1 receptor antibody|dopamine receptor D1 antibody|DR D1 antibody|DR D1A antibody|DRD 1 antibody|DRD 1A antibody|DRD1 antibody|DRD1_HUMAN antibody|DRD1A antibody
    UniProt
    P21728
    途径
    cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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