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ANXA6 抗体 (C-Term)

This anti-ANXA6 antibody is a 兔 多克隆 antibody detecting ANXA6 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3044399
发货至: 中国

Quick Overview for ANXA6 抗体 (C-Term) (ABIN3044399)

抗原

See all ANXA6 抗体
ANXA6 (Annexin A6 (ANXA6))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ANXA6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 636-652, C-Term

    原理

    Anti-Annexin VI/ANXA6 Antibody Picoband®

    序列

    NIRREFIEKY DKSLHQA

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Annexin VI/ANXA6 Antibody (ABIN3044399). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Annexin VI, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat, Human, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Davies, A. A., Moss, S. E., Crompton, M. R., Jones, T. A., Spurr, N. K., Sheer, D., Kozak, C., Crumpton, M. J.The gene coding for the p68 calcium-binding protein is localized to bands q32-q34 of human chromosome 5, and to mouse chromosome 11.Hum. Genet. 82: 234-238, 1989. 2. Smith, P. D., Davies, A., Crumpton, M. J., Moss, S. E.Structure of the human annexin VI gene.Proc. Nat. Acad. Sci. 91: 2713-2717, 1994. 3. Thomas, D. D. H., Kaspar, K. M., Taft, W. B., Weng, N., Rodenkirch, L. A., Groblewski, G. E.Identification of annexin VI as a Ca(2+)-sensitive CRHSP-28-binding protein in pancreatic acinar cells.J. Biol. Chem. 277: 35496-35502, 2002.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ANXA6 (Annexin A6 (ANXA6))

    别名

    ANXA6

    背景

    Synonyms: Annexin A6,67 kDa calelectrin,Annexin VI,Annexin-6,Calphobindin-II,CPB-II,Chromobindin-20,Lipocortin VI,Protein III,p68,p70,ANXA6,ANX6,

    Background: Annexin A6 (ANXA6) is a member of a family of proteins that bind membrane or cytoskeleton in a Ca (2+)-dependent manner. These proteins are characterized by homologous amino acid sequences that are present in multiple copies in each protein. ANXA6 gene is assigned to 5q32-q34 by use of a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids and for in situ hybridization.The ANX6 gene is approximately 60 kb long and contains 26 exons. The genomic sequence at the 3-prime end does not contain a canonical polyadenylylation signal.Ca (2+)-dependent binding between CRHSP28 and ANXA6 is required for acinar cell membrane trafficking events and digestive enzyme secretion

    Sequence Similarities: Belongs to the annexin family.

    分子量

    45 kDa

    UniProt

    P08133
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