Muscarinic Acetylcholine Receptor M2 抗体 (C-Term)
Quick Overview for Muscarinic Acetylcholine Receptor M2 抗体 (C-Term) (ABIN3044369)
抗原
See all Muscarinic Acetylcholine Receptor M2 (CHRM2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 356-370, C-Term
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原理
- Anti-Muscarinic Acetylcholine Receptor 2/CHRM2 Antibody Picoband®
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序列
- EKQNIVARKI VKMTK
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Muscarinic Acetylcholine Receptor 2/CHRM2 Antibody (ABIN3044369). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Muscarinic Acetylcholine Receptor 2, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) antibody
CHRM2 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1424CT461-78-60 unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) antibodyCHRM2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 381-466) antibodyCHRM2 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 208-388) antibodyCHRM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) (Cytoplasmic Domain) antibodyCHRM2 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, Pig, 绵羊, 兔, 马, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) (Cytoplasmic Domain) antibodyCHRM2 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, Pig, 绵羊, 兔, Hamster, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) (Cytoplasmic Domain) antibodyCHRM2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 251-350) antibodyCHRM2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B5 unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 3-20) antibodyCHRM2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 352-364) antibodyVerified CHRM2 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: CHRM2 cholinergic receptor, muscarinic 2". 2. Comings DE, Wu S, Rostamkhani M, McGue M, Lacono WG, Cheng LS, MacMurray JP (January 2003). "Role of the cholinergic muscarinic 2 receptor (CHRM2) gene in cognition". Mol. Psychiatry. 8 (1): 10-1. 3. Gosso MF, van Belzen M, de Geus EJ, Polderman JC, Heutink P, Boomsma DI, Posthuma D (November 2006). "Association between the CHRM2 gene and intelligence in a sample of 304 Dutch families". Genes Brain Behav. 5(8): 577-84. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
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别名
- CHRM2
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背景
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Synonyms: Muscarinic acetylcholine receptor M2,CHRM2,
Background: The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
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分子量
- 45 kDa
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UniProt
- P08172
抗原
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