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IFITM1 抗体 (N-Term)

IFITM1 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044336
发货至: 中国
  • 抗原 See all IFITM1 抗体
    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
    抗原表位
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-17, N-Term
    适用
    • 49
    • 5
    • 5
    宿主
    • 44
    • 4
    • 1
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 29
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFITM1 antibody is un-conjugated
    应用范围
    • 36
    • 23
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Rabbit IgG polyclonal antibody for Interferon-induced transmembrane protein 1(IFITM1) detection. Tested with WB, IHC-P, IHC-F in Human.
    序列
    MHKEEHEVAV LGPPPST
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Interferon-induced transmembrane protein 1(IFITM1) detection. Tested with WB, IHC-P, IHC-F in Human.
    Gene Name: interferon induced transmembrane protein 1
    Protein Name: Interferon-induced transmembrane protein 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human IFITM1(1-17aa MHKEEHEVAVLGPPPST).
    亚型
    IgG
    Top Product
    Discover our top product IFITM1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Ma, Zhang, Fu, Xia, Zhan, Li, Wang, Wu: "Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." in: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).

    Xu, Yang, Hu: "Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation." in: Acta biochimica et biophysica Sinica, Vol. 41, Issue 6, pp. 488-94, (2009) (PubMed).

    Yang, Xu, Chen, Hu: "IFITM1 plays an essential role in the antiproliferative action of interferon-gamma." in: Oncogene, Vol. 26, Issue 4, pp. 594-603, (2007) (PubMed).

  • 抗原
    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
    别名
    IFITM1 (IFITM1 产品)
    别名
    9-27 antibody, CD225 antibody, DSPA2a antibody, IFI17 antibody, LEU13 antibody, 1110036C17Rik antibody, Mil-2 antibody, Mil2 antibody, interferon induced transmembrane protein 1 antibody, interferon induced transmembrane protein 1 (9-27) antibody, Ifitm1 antibody, IFITM1 antibody
    背景
    Interferon-induced Transmembrane Protein 1(IFITM1), also called Interferon-induced Protein 17(IFI17). IFITM1 activity is required for primordial germ cells(PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins(Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth.

    Synonyms: 9-27 antibody|CD 225 antibody|CD 225 antigen antibody|CD225 antibody|CD225 antigen antibody|Dispanin subfamily A member 2a antibody|DSPA2a antibody|IFI 17 antibody|IFI17 antibody|IFITM1 antibody|IFM1_HUMAN antibody|Interferon induced protein 17 antibody|interferon induced transmembrane protein 1(9-27) antibody|Interferon induced transmembrane protein 1 antibody|Interferon inducible protein 9-27 antibody|Interferon-induced protein 17 antibody|Interferon-induced transmembrane protein 1 antibody|Interferon-inducible protein 9-27 antibody|Leu 13 antibody|Leu 13 antigen antibody|Leu-13 antigen antibody|LEU13 antibody
    UniProt
    P13164
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