IFITM1 抗体 (N-Term)
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北京 101111
Quick Overview for IFITM1 抗体 (N-Term) (ABIN3044336)
抗原
See all IFITM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-17, N-Term
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原理
- Anti-IFITM1 Antibody
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序列
- MHKEEHEVAV LGPPPST
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-IFITM1 Antibody (ABIN3044336). Tested in IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human IFITM1.
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亚型
- IgG
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anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (C-Term) antibody
IFITM1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) antibodyIFITM1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (AA 1-125) antibodyIFITM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (AA 1-36) antibodyIFITM1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (AA 37-66) antibodyIFITM1 适用: 人 WB 宿主: 兔 Polyclonal RB40554 unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (N-Term) antibodyIFITM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (AA 1-125) antibodyIFITM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (AA 1-125) antibodyIFITM1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (Internal Region) antibodyIFITM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) (Center) antibodyIFITM1 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." in: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).
: "Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation." in: Acta biochimica et biophysica Sinica, Vol. 41, Issue 6, pp. 488-94, (2009) (PubMed).
: "IFITM1 plays an essential role in the antiproliferative action of interferon-gamma." in: Oncogene, Vol. 26, Issue 4, pp. 594-603, (2007) (PubMed).
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: "Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." in: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).
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- IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
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别名
- IFITM1
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背景
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Synonyms: Interferon-induced transmembrane protein 1,Dispanin subfamily A member 2a,DSPA2a,Interferon-induced protein 17,Interferon-inducible protein 9-27,Leu-13 antigen,CD225,IFITM1,CD225, IFI17,
Tissue Specificity: Bone (at protein level). Levels greatly elevated in colon cancer, cervical cancer, esophageal cancer and ovarian cancer. Expressed in glioma cell lines. .
Background: Interferon-induced Transmembrane Protein 1 (IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth.
Sequence Similarities: Belongs to the intermediate filament family.
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分子量
- 70-74 kDa
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UniProt
- P13164
抗原
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